The Health Benefits of Probiotics for Dogs

by Narelle Cooke, Canine Nutritionist

"Just call me Doggocrates."

Over 2000 years ago Hippocrates stated that “all disease begins in the gut” – a concept that has well and truly stood the test of time. In the last few decades, research has started to catch up with this traditional wisdom and recognise that a healthy gut is largely responsible for good overall health for both us and our dogs. Unfortunately, just as gastrointestinal diseases are a major cause of illness in people,(1) poor digestive health also plagues many dogs, with the research showing that gastrointestinal problems are the primary reason for vet visits (2).

As a natural healthcare practitioner, I see the consequences of compromised digestion on a daily basis, along with the impact that this has on many other facets of health, including:

Impaired immune function

Food and environmental allergies

Gastrointestinal tract infections

Behavioural problems (including anxiety)

The great news is, that there is increasing scientific evidence to support the incorporation of probiotics (live beneficial bacteria and yeasts) into our dogs’ diets as a means to derive a wide range of health benefits. For example, studies show that probiotics can help to:

Aid digestion

Support the immune system

Reduce gastrointestinal issues

Reduce allergic reactions

Promote nutrient production

Enhance nutrient absorption

Eliminate toxins from the body

Support skin health

Positively influence mood and stress-related behaviours

The critical importance of gut barrier function

One of the main mechanisms by which probiotics are able to deliver such amazing health benefits is due to their positive impact on the gut lining. By strengthening the mucosal barrier, it reduces the transfer of toxic compounds into the dog’s body and promotes stronger immune function. A healthy gut barrier also supports increased mucosal antibody production which helps to protect against infection, and also acts to suppress the growth of potentially pathogenic bacteria.

Conversely, any disturbance of gut barrier integrity can lead to increased permeability – aka ‘Leaky Gut’. This results in bacterial endotoxins, insufficiently digested food particles, and other immunomodulatory components entering more easily into the blood stream, where they are linked with an increase in various systemic inflammatory disorders (3). Unfortunately, many common dietary and lifestyle factors that our dogs are exposed to are known to cause leaky gut and damage our dog’s resident microbiota. Key examples include:

• Acid-lowering medications such as proton-pump inhibitors, antacids and histamine-2-antagonists. Such drugs are consistently linked with profound changes in the gut microbiota (4). They have also been associated with an increased risk of enteric infections (5,6).

• Anti-inflammatory medications such as non-steroidal anti-inflammatory drugs, which are a common causes of acute gastric erosion and chronic gastric ulceration (7).

• Antibiotics which cause rapid and significant drops in microbial numbers and diversity, the effects of which can persist for months or even years. Beyond increasing the immediate risk for infection, microbiota alterations caused by antibiotics can also affect basic immune balance with long-term repercussions (8).

The beneficial role of spore-forming bacteria – the new kids on the block!

"Tummy rubs definitely help with probiotic absorption."

Throughout history, human beings have consumed spore-based probiotics through the ingestion of raw vegetables and fermented foods that are contaminated with soil microflora. Unlike most traditional probiotics, which are similar to those found naturally in the gastrointestinal tract, spore-based probiotics derived from Bacillus species are among the most widespread microorganisms in nature and are able to grow under extreme environmental conditions such as high temperatures, high humidity, extreme drying and different types of radiation. Such resilient properties also allow them to resist those aspects of the body that are naturally designed to have an anti-microbial effect, such as gastric acid, pancreatic enzymes, and bile.  Such robustness of spore-forming bacteria results in a greater number of spores reaching their destination in the intestines, where they then revert to active, growing bacteria that have been shown to support health in several ways.

Recent studies on Bacillus subtilis highlight its numerous health benefits (9-17).

Probiotic species Key health benefit for dogs
Bacillus subtilis • Producing antibiotic substances against pathogenic bacteria
• Antidiarrheal effects
• Enzyme production
• Reducing inflammatory cytokines
• Immune-stimulatory effects
• Prevention of intestinal inflammation
• Improvement in gut-barrier integrity
• Regulation of bowel movement frequency
• Improved neurochemical activities
• Reduction in aggressive behaviour
• Normalisation of intestinal flora
• Prevention of gastrointestinal disorders
• Reduction in gas formation
• Reduction in faecal odour

Why increased diversity is key

It has been said that 'the whole is greater than the sum of its parts', and this is especially true of probiotics, where the functional role of the bacterial community is often more important than the individual components. Research investigating a wide range of disorders (including irritable bowel syndrome, diarrhoea, atopic disease – which may manifest as itchy skin and allergies in our pets, immune function, respiratory tract infections, and inflammatory bowel disease) has demonstrated that multi-strain probiotics confer greater efficacy than probiotics that contain only single strains.

And just as different types of microorganisms can cause different types of illnesses, different types of probiotics have different positive effects on a dog’s body.  For example, other beneficial probiotic species to include in your dogs’ daily routine include (18-27):

Probiotic species Key health benefit for dogs
Enterococcus faecium
• Stimulates immune function
• Lessens duration of acute diarrhoea
• Improves stress-related diarrhoea
• Reduces pathogenic bacteria
Lactobacillus acidophilus • Reduces diarrhoea
• Reduces pathogenic bacteria
• Stimulates immune function
• Improves nutritional status
• Improves faecal parameters
• Strengthens intestinal barrier
Bifidobacterium longum • Reduces anxiety
• Reduces pathogenic bacteria
• Improves intestinal health
• Reduces gastrointestinal disorders
Saccharomyces cerevisiae • Improves stool frequency and stool consistency
• Reduces symptoms of chronic enteropathies
• Reduces pathogenic bacteria
• Enhances immune function
• Reduces inflammation
• Improves nutrient digestibility

Probiotic supplement or probiotic-rich food – which to choose?

"So many options...must research all avenues."

Both probiotic supplements and probiotic-rich foods can be highly beneficial to overall health and are great additions to our dog’s diets, but I often get asked if one is better than the other.

The World Health Organization defines probiotics as “live microorganisms which when administered in adequate amounts confer a health benefit on the host”. Therefore, in order to be labelled a probiotic, there needs to be documented scientific evidence for the health benefit – which is where probiotic supplements and probiotic-rich foods tend to differ the most. But to help shed further light on the matter, lets’ look at some key advantages and disadvantages of each.

Probiotic Supplements
Advantages Disadvantages
• Have a documented health benefit.
• Allow greater control over the specific type and number of bacterial species that you give your dog, which can be important when it comes to addressing particular health issues.
• Allow easy dosing of extremely high numbers of bacteria, which can act to increase their efficiency.
• Free of common allergens such as wheat, gluten, dairy and soy.
• May cause transient gastrointestinal upset in the beginning if high doses given.
• Can be expensive when given long-term.
• The number of live bacteria can be reduced if not stored correctly.

Probiotic-Rich Foods
Advantages Disadvantages
• Provide additional beneficial nutrients rather than just probiotics alone.
• Often contain sources of fibre which act as prebiotics (the food source to the probiotics).
• Can contain a wider diversity of bacterial strains compared to supplements.
• Probiotic bacteria must be alive at the time of consumption to provide any benefit. Food processing methods such as heat-treatments, pasteurisation and extended storage times can negatively affect bacterial survival.
• Fermented foods can have a strong flavour and smell that is off-putting to many dogs.
• Fermented foods can worsen allergies by stimulating histamine release.
• Many dogs do not tolerate dairy-based foods.
• There is limited evidence surrounding the number, type and benefits of bacteria present in certain foods.

Quick decision-making checklist

While many situations support the use of both probiotic supplements and probiotic-rich foods at the same time, the table below highlights those instances in which a probiotic supplement should take priority in the support of your dog.

Situation Probiotic Supplement Probiotic-rich Food
I know my dog tolerates fermented- and dairy foods
My dog is consuming kibble on a daily basis
My dog is currently on acid lowering medications
My dog has a history of antibiotic use
My dog is prone to diarrhoea
I need to address a specific health problem in my dog
My dog suffers from allergies

If your dog is currently healthy, you might consider including probiotics in the diet intermittently. For example, administer every few days as a means to give their gastrointestinal and immune systems a healthy boost. And if your dog has a condition noted above that may benefit from probiotic use, consider administering probiotics daily for at least 8 weeks while continuing to monitor their symptoms.


Imbalanced gut microflora (often referred to as ‘dysbiosis’), disrupts overall health and wellness. There is growing evidence to support the use of probiotics for both dogs and cats. Giving your pet healthy bacteria may positively influence chronic gastro-intestinal conditions such as IBS and IBD, obesity, liver disease, dental disease and behavioural disorders. A daily probiotic supplement may also provide additional benefits, such as improved appearance and quality of the skin and coat, a reduction in intestinal gas, improved breath, a reduction of allergies and in yeast-associated disorders, and improvements in bowel regularity and consistency.

Probiotics are generally considered safe for dogs and usually don’t cause any side-effects. But as every dog is created differently, always monitor your dog when starting them on anything new.

About the Author - Narelle Cooke, Canine Nutritionist.

Narelle is a clinical Naturopath, Nutritionist and Herbalist for both people and pets, and operates her wellness clinic ‘Natural Health and Nutrition’ in Dural, Sydney.

Being a lifelong dog-owner and currently meeting the demands of three French Bulldogs, two German Shepherds and a Burmese cat, Narelle is as passionate about the health and wellbeing of our pets as she is about their owners. And it was this strong desire to see her own pets live their longest and best lives that led her to hours of personal research and additional study in the area of natural animal health and nutrition.

·  Bachelor of Health Science(Naturopathy) (ACNT)
·  Bachelor of Agricultural Science (honours) (The University of Melbourne)
·  Advanced Diploma of Naturopathy (AIAS)
·  Advanced Diploma of Nutritional Medicine (AIAS)
·  Advanced Diploma of Western Herbal Medicine (AIAS)
·  Certificate III in Dog Behaviour and Training (NDTF)
·  Certificate in Natural Animal Nutrition (CIVT)
·  Certificate in Animal Nutrition (HATO)

1. Australian Institute of Health and Welfare, Australia's health 2012, in Australia's Health Series, No. 13.(Cat. no. AUS 156.). 2012.
2. Rakha, G.M., Abdl-Haleem, M.M., Farghali, H.A., et al. (2015). Prevalence of common canine digestive problems compared with other health problems in teaching veterinary hospital, faculty of veterinary medicine, cairo university, egypt. Veterinary World, 8(3): p. 403-411.
3. Leech, B., Schloss, J., and Steel, A. (2018). Association between increased intestinal permeability and disease: A systematic review. Advances in Integrative Medicine, 6(1): p. 23-34.
4. Imhann, F., Bonder, M.J., Vich Vila, A., et al. (2016). Proton pump inhibitors affect the gut microbiome. Gut, 65(5): p. 740-748.
5. Leonard, J., Marshall, J.K., and Moayyedi, P. (2007). Systematic review of the risk of enteric infection in patients taking acid suppression. Am J Gastroenterol, 102(9): p. 2047-2056.
6. Janarthanan, S., Ditah, I., Adler, D.G., et al. (2012). Clostridium difficile-associated diarrhea and proton pump inhibitor therapy: A meta-analysis. Am J Gastroenterol, 107(7): p. 1001-1010.
7. Webb, C. and Twedt, D.C. (2003). Canine gastritis. Veterinary Clinics of North America: Small Animal Practice, 33(5): p. 969-985.
8. Francino, M.P. (2015). Antibiotics and the human gut microbiome: Dysbioses and accumulation of resistances. Front Microbiol, 6: p. 1543.
9. Sorokulova, I. (2013). Modern status and perspectives of bacillus bacteria as probiotics. Journal of Probiotics & Health, 1(4): p. 1-5.
10. Paap, P.M., Van Der Laak, J.H., Smit, J.I., et al. (2016). Administration of bacillus subtilis c-3102 (calsporin®) may improve feces consistency in dogs with chronic diarrhea. Research Opinions in Animal & Veterinary Sciences, 6(8): p. 256-260.
11. Lefevre, M., Racedo, S.M., Denayrolles, M., et al. (2017). Safety assessment of bacillus subtilis cu1 for use as a probiotic in humans. Regulatory Toxicology and Pharmacology, 83: p. 54-65.
12. Rhee, K.J., Sethupathi, P., Driks, A., et al. (2004). Role of commensal bacteria in development of gut-associated lymphoid tissues and preimmune antibody repertoire. J Immunol, 172(2): p. 1118-1124.
13. Lefevre, M., Racedo, S.M., Ripert, G., et al. (2015). Probiotic strain bacillus subtilis cu1 stimulates immune system of elderly during common infectious disease period: A randomized, double-blind placebo-controlled study. Immun Ageing, 12: p. 24.
14. Huang, J.M., La Ragione, R.M., Nunez, A., et al. (2008). Immunostimulatory activity of bacillus spores. FEMS immunology and medical microbiology, 53(2): p. 195-203.
15. Hong, H.A., Duc Le, H., and Cutting, S.M. (2005). The use of bacterial spore formers as probiotics. FEMS Microbiol Rev, 29(4): p. 813-835.
16. Bastos, T.S., De Lima, D.C., Souza, C.M.M., et al. (2020). Bacillus subtilis and bacillus licheniformis reduce faecal protein catabolites concentration and odour in dogs. BMC Vet Res, 16(1): p. 116.
17. Cuentas, A.M., Deaton, J., Davidson, J., et al. (2017). The effect of bacillus subtilis de111 on the daily bowel movement profile for people with occasional gastrointestinal irregularity. Journal of Probiotics & Health, 5(4): p. 1-4.
18. Benyacoub, J., Czarnecki-Maulden, G., Cavadini, C., et al., Supplementation of food with enterococcus faecium (sf68) stimulates immune functions in young dogs, in International Symposium on Enterococci in Foods, Functional and Safety Aspects. 2002: Berlin, Germany.
19. Gore, A.M. and Reynolds, A. (2012).Effects of enterococcus faecium on stress diarrhea. . in ACVIM Forum Proceedings.
20. Nixon, S.L., Rose, L., and Muller, A.T. (2019). Efficacy of an orally administered anti-diarrheal probiotic paste (pro-kolin advanced) in dogs with acute diarrhea: A randomized, placebo-controlled, double-blinded clinical study. J Vet Intern Med, 33(3): p. 1286-1294.
21. Baillon, M.L., Marshall-Jones, Z.V., and Butterwick, R.F. (2004). Effects of probiotic lactobacillus acidophilus strain dsm13241 in healthy adult dogs. Am J Vet Res, 65(3): p. 338-343.
22. Moarelli, S.P., Fusi, E., Alberto, G., et al. (2020). Effects of probiotic lactobacillus acidophilus d2/csl (cect 4529) on the nutritional and health status of boxer dogs. Veterinary Record: p. 1-6.
23. Kainulainen, V., Tang, Y., Spillmann, T., et al. (2015). The canine isolate lactobacillus acidophilus lab20 adheres to intestinal epithelium and attenuates lps-induced il-8 secretion of enterocytes in vitro. BMC Microbiol, 15(4): p. 1-8.
24. Park, H.E., Kim, Y.J., Do, K.H., et al. (2018). Effects of queso blanco cheese containing bifidobacterium longum kacc 91563 on the intestinal microbiota and short chain fatty acid in healthy companion dogs. Korean J Food Sci Anim Resour, 38(6): p. 1261-1272.
25. D'angelo, S., Fracassi, F., Bresciani, F., et al. (2018). Effect of saccharomyces boulardii in dog with chronic enteropathies: Double-blinded, placebo-controlled study. Veterinary Record, 182(9): p. 258.
26. Lin, C.Y., Alexander, C., Steelman, A.J., et al. (2019). Effects of a saccharomyces cerevisiae fermentation product on fecal characteristics, nutrient digestibility, fecal fermentative end-products, fecal microbial populations, immune function, and diet palatability in adult dogs. J Anim Sci, 97(4): p. 1586-1599.
27. Franklin, R.P. and Latson, K.M., Saccharomyces boulardii probiotic for pets(white paper).

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